CN Bio to bring 10 organs together on a chip

London Organ-on-Chip specialist CN Bio announced it has secured an exclusive license to technology from the Massachusetts Institute of Technology for Organ-on-Chip systems which connect human tissues from up to 10 organs.

CN Bio participated with MIT on a US$26M DARPA federal contract to develop a Human-Body-on-Chip system. In an article published in Nature Scientific Reports in March 2018, MIT researchers and CN Bio announced the successful final milestone of this program to bring 10 organs together on a chip.

CN Bio CEO Dr David Hughes said:

Scientists currently lack adequate means to determine whether a new drug to treat one organ is likely to have adverse effects on another. At present much of this information comes from poorly predictive animal studies. Many costly drug failures take place because we lack the ability to generate human relevant data in the laboratory – this is exactly the data which our PhysioMimix Multi-Organ-on-Chip studies will provide.

These MIT patents extend our portfolio to cover multi-organ systems. We believe multi-organ safety and efficacy studies can bridge a serious gap in drug development between simple pre-clinical in vitro tests and difficult and expensive animal testing.

By recreating human organ interactions on CN Bio’s smart-phone sized chip, scientists can measure the effects of drugs or other chemicals on different tissues of the body.

The CN Bio team is building the multi-organ consumable plates to be compatible with its award-winning PhysioMimix benchtop Organ-on-Chip system.